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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef8e219347f496183e44307cb88ef38c18407bd91b57ee57b4d7817872c9904' 
  AND token = 'tI1hMl0hzLphpfEBQlnH6aXKyRMNVRoouoVsSqLEcUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}