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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cab72978365be23708f2c958e2615bdb8b8edc6b0f4fe5bf43d392e555587f40' 
  AND token = 'buwaFTa3eP93SC3bUpDV6I/1UlT0fpS/ZERKPvYMTO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}