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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521ba7c7bf527fda25e6822c03f11d9233806f3db37270ac662c754a6195e5f5' 
  AND token = 'rSauifFfyrqA7lnehiAlC6FBBjYFGfJ5K/YaK4oKrCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}