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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f4041d7372b19168ba36a0454f80aacff30fe260c1e9ea25d291c1dc395fff' 
  AND token = 'PJXmM4n7X739Yv3rBaMk3C08ku7+1jfeoE+bcAV2bDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}