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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2210479848166cd39fd6be5aa67639df87754273e942e94e2832f61bb1fc4a5' 
  AND token = 'Lqwi2ATAYrzQ0Y8b4foJu7DYJAjnuRhIfa2IqCJsShk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}