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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0450aaace207f8af5c543eb724e1c1a6e519a938c8aa5d2930033890b592365' 
  AND token = 't8LnptM6lv1WznGncc26Q1g3OeuU8eXe0jcgSfPML34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}