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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f4ad4516f64abfdabda27c1457dec95764e5d398e4bbd4a07910a948645d22' 
  AND token = 'AsK+H73KXBeFXhMTtNlUXlo0WPW5FUnATf4RFT3twZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}