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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56a1b187091da8eac7cd6367de3e6906d2309ff1c7611200f2c6b062311c6b2b' 
  AND token = '7QiZWy7U6khjxemDrmyDkHJxs4nM9CVR5VDH7PuqXWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}