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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cfe8c8930a3f2c1479c92e9f9b17a4b738989f0ecdfe01926cb5d6ed914dee' 
  AND token = 'IAIDPupy/gKTdiONWN6LbwU0rM1p+usknmqP9jPKtGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}