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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a25ed087cc656e367c52dd693a66a5878c8f298d7bf9241dc3a04677f72cea' 
  AND token = '1hR7mrbvUvzPLpQ6NFiopvyMY92PfUyJ5/XHYxtmwiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}