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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bcd789cd93b6064f12818242487763eab41e69c47843f8feea99589682b36db' 
  AND token = 'OV+6QAq44RQs8ECMHT7yxDkqBSwdQIgVXWvyQn1yAnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}