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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e8932d11d57e95170d39f69e2bb23b11bad43125c1c178471e0810a41a0331' 
  AND token = 'JPGCFnyq3DBGqeUz5KNSpt/p3cMS+dE2zBnzd2kNyd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}