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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33329ed89e65df045112d2c472356f1366f3e2e80d4dd8587ace5a4466a0cd6' 
  AND token = 'vpvKhZyixQc25xyuAyxcZ/oc6JHaJvOIA1j3FPhsrZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}