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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d982bbf410aee4be155690b12fbc50b228c3cb1b1411f9624067daa79eb3aad' 
  AND token = 'kNkjPbQA0A9m+c7/N1RcIhKt3eWilmbtOGrLrPu4srE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}