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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16e08b428538e80c145a773ab2e49b7d10235477e3689ddb3e8eaad1bc2cae6' 
  AND token = 'jbO0VZKAp+MbaD2iHGWyuMHyPQaPjNeJOgYT2Ir66cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}