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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bf8e7437b5289527ff73dddfe2735822f297a3415a6b76d0848ad69c8bba08e' 
  AND token = 'IcM4gXOZA3CMMeb6oTgO/qgIlSilevWkuTjUgqzmBq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}