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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e3e3c8b7806b204d44191cbb3f08beaee91b3c807acdef5b674db077f21488' 
  AND token = 'SiMfbJl159Om2UDJshZhHnRbCa9OVxf9pGZvawPuwwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}