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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7725b08ff44cbbdd39f201e2b5bffc372c6591c07c2015abc91a58f8f90d1985' 
  AND token = 'mh/w+NUk2UreNHS655p18oK12AO55bblifn6Q2RuLls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}