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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e029071330c59ecdd8cd76a94a421b280e72444270e3bddf7bea6df19d6f852c' 
  AND token = 'pXmY0YoDGsTzXaUx1m8CzcMFftYhBllUMF3d4GG+vqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}