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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906cef8f29513450d0f7ae8b8893ea6ce1fdc01d7af02e982a40a2e4e3663907' 
  AND token = 'zTPsQV01HQU7IzmrLwdy5MtYYfH+WzwpEUCuFPEGPrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}