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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eacce02d796b376932d5e3b057a6781f9bdc9d00ab5e91dd45f86275af2be71' 
  AND token = 'oLqGt5n/P0eJTXr1FXWn12hhDcKWEaz1xIJ2FwJfscc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}