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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757e95babab83ef6199e696f4d40bf6a5f27fc36090dff22bf90d92976e5af4e' 
  AND token = '+grLIfpxpfh9+Ktojo2veS0H92460C9RO2r/27j15IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}