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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f1aae34939c85745426f935a7d8da7fc36be896e101016ae854dcb0dac9afa' 
  AND token = 'sWteTKchKMBx/M/80Lo3euq55CYZjdbgbt9Qc11z3TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}