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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6e1bfa0285abf5f6368043107826872a67369dc92d990dc16aa8f8c5e3b292' 
  AND token = 'sOm+/yyShW1pZLSsCdeqI9ThN/SfH/lmcOcAYBd2rlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}