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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5213dc22975af7118a1743eed247f72ede801743b0e0bd1f60aab1712da82a76' 
  AND token = 'qsx2KxHm9x1ERF8Q+l/GZt914lPSQ7G9p5djSAm7s9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}