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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54188dec34cbb5c893c103bea707321376c25b57b1e15daea0466add5bc7d46' 
  AND token = 'wyIDGycO+yIB5dx9Dw+SnPfAq/MmYuYvfCfiTTDpPps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}