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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da3b1a0f27cd51fd961c5078ff342da627e611b621af76f7339aa1d7aa89512' 
  AND token = 'j0TCOH7PZDXjk96AQYB+3TkUcHsjcKlQZMzmXzcay4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}