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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853fe4261d9d752fb69a851b55427cb94b84c44dbe00a04bf4a1b51f2dbd7060' 
  AND token = 'mPS9pUiptYVqdcMRpr82rS6kS4uiwH377+abgrwYzUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}