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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db2145dc3ad32539d4945ee5f27ea437c679c95e04d3adb471d024a46f9e292' 
  AND token = '2Qhx6ftSiDogWOguHQG4WtLNI5RP4KrmgeIwUVsU4xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}