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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c22516c3532a153134feb24259cf5b38640d4072852d72175295ed6598fa20' 
  AND token = 'OsiK1aIH8Lz1wDLT1RHhE5nKJUer0uC/BKABq1fsl9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}