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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2803f33449084b44feaf2106dc18cac32fcd79bfa43dcd23fbee92dd9ced4f0d' 
  AND token = 'gBeYdJ6C9J+r0DTot1+y/TJEMQ1srmTt3+ONKpeLGXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}