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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e82a2cca0cf16d49501fd7b1253d6438d1cbb47f571d3e575414732211a3dc3f' 
  AND token = 'uk7RCbdYrk1fSa7uTF8i7A2F8DYe9PYL9F9ClFuKP6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}