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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a484259c46d4f252ea2752f1fe64727235b14fa3a4e2fcf0191bd83232a399f1' 
  AND token = 'nykHU260/3SEs4j7ewAD3pk1TQZODROz4QSLgnVsgII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}