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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5621253ef28a074f7dbd5c0624f0d87fbfb529e830bca821bec693e6f3c8b5b3' 
  AND token = 'EguiXE9OMWfcY1fpiHRJ3AqSIwtwbD4ooCyO6o1rX5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}