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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e678229c76d27e25f84158bba1651257d60f5dffe993e26869cd68908fe247' 
  AND token = '4P8//VwgF+n6SnNbWfeYIFS+ULzdR9KzbFFXEWiUepY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}