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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5582d2beb03e77c247431c832c8605a32532934085253f537168e164a52152ee' 
  AND token = 'PlQ3JUgz19cXVvd7HJMNmwINsl6HA1v+vaSrg7ymz7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}