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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd995cbb2fff57a138ed16d6c5e2c9d62c1a0c233aef92bd1712898d9de494c' 
  AND token = 'SaYOtN1BWP87/D3S9q9OXw+rD31Wv9fxbNHE+NCmoQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}