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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc2e5def6087a5a8cad7d70692609ecca36931cffba9c6ac0632e036d2aa906' 
  AND token = 'bqXnZJVaA+0V6WGTDIxS3fRiGpFtFCbZEjn0vSnHrsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}