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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf13ba740bfe2b7bc1d01e7e253218423ea988ea3da8d733800cf61e4a905538' 
  AND token = 'WpcO/uWaKmnHjOVI8jQZ/5XvtfwUHgqoU74Vy9c1Y1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}