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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a79fda4dd21f196a0dcaf33d133ffaebe27d0ef25e66014b1d9ac451cabdf936' 
  AND token = 'vIGsO58pZ5RJxMVjIuqg6UceV3oEgyZKpJ/sLMQpdhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}