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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d378a5955743d662fcb520dfd7c8fbb502921e1f542199167562345dc1d7fbd' 
  AND token = 'S1zUUcFGQj7C/x5JRpMRezTzA1Ea0Fq+N74auKqCiHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}