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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d45b5c2f0e3e0d91858694d6d92abfe7646abf6940fb3562265eaba1c22d78' 
  AND token = 'hvAFz7qbevOgdqBNqJjg2hDPBUccWE0oyydrwHi8w3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}