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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0117501e3711bf5ed3628bd4ba9ce1933c8f8e0faa43e76b023155205609d52' 
  AND token = 'OBnKUSDkY/h99b5lMUJCWurzsc0fT8A9HdSoffHrFb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}