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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5529baff64c2216ecec6241c9ed71e68e61d3cfec52550fb9898f22cfd7cd69a' 
  AND token = '+dp17LUw3sI9ESGA8VMKHAdS4xvAY4BG/yBGaoqaaGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}