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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13ef5ce789f5a49a37045dc17efd7dece5b3cd10894216de4e9f36d872e686fe' 
  AND token = '15t+h7trzSR+5D6f//XhVKkShg3PjgaAghJHQQz70LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}