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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3680296ebc60de11ddc80b9affad8308db9a6e5e89a057dabbe9157e361a2b5' 
  AND token = 'TqE3S9M8jJ2gtSUDuT6tBKyaDpUsbxeKBw3j44UXbqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}