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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd0d9be11e6668c95b397fbaeb2ca172f28fcded5aa004ac51922461760d4b70' 
  AND token = 'H1eK6+9RC6xOGXwo+hlRiLPBI7bSJO9bvC2Ng8tH4LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}