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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c200a7919b208e421a422505b6f2bd2a1654e1474a75a247ee1a4f0ce81adb54' 
  AND token = 'KMHS2VN0W6TC7NQu2iUE7XHahR8Zl8tV5/OuaF44GLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}