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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '255d24c7455e3931edd021da793b98846849d647d750a87fcabdf3b5a352eb05' 
  AND token = 'VG1nfTNpF4S97Tk4pH6nGAct3hCxKFqvm8kYO+4dDRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}