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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5fc0dd00770f8d2b28da356021d4f5dd342953318c69b729fff7a713076625' 
  AND token = 'X3RCO44LawU+AUjwHZjdte4PA0VFu66iGxaK5LKmk7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}